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1, 8-cineole ameliorates colon injury by downregulating macrophage M1 polarization via inhibiting the HSP90-NLRP3-SGT1 complex

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90 VakifahmetogluH.OlssonM.ZhivotovskyB

This is further supported by Zhang et al., who demonstrated that impairing the GLO pathway specifically disrupts the production of Kce and Kd-la, while the generation of lactyl-CoA appears to be positively correlated with Kl-la [18] (Fig