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Miyake, Biochemistry and biological functions of citrus limonoids, Food Rev

For tumour xenograft experiments, athymic nude NU/J mice (The Jackson Laboratory, 002019) were used (female, at least 8 weeks old)

Variability: Responses may differ across species, tissue types, and experimental conditions

Similarly, they have also modulated parameters linked with adipose tissue reduction, wound healing, and neuroprotection in organisms during clinical studies

[135] During the Million Hearts (MH) model (which was tested from 2017-2022), there was a recently-introduced ASCVD risk assessment tool to incorporate demographic (age, sex, race), clinical (blood pressure, cholesterol, history of diabetes), and risk behavior (smoking status, use of anti-hypertensives, use of statins, use of aspirin) established by the American College of Cardiology (ACC), [136] as well as a longitudinal re-assessment tool used within the model