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The only controlled study in trained athletes ( Mechanistic implications for endurance athletes Inhibiting mitochondrial fatty-acid uptake acutely forces a greater reliance on glucose and glycogen during exercise

This could primarily be allocated to the pivotal role of insulin in regulating carbohydrate and lipid metabolisms, but also to the involvement of many of these intermediates in bidirectionally modulating insulin production and signaling (e.g., influence of hyperglycemia in the development of IR, lipotoxicity induced by acyl-carnitines and FFAs) [4]

J Trace Elem Med Biol 48:172180

Dec 8 2020;doi:10.2174/1874467213666201209105005 Marx W, McKavanagh D, McCarthy AL, et al

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