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Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure

Excess B vitamins are excreted by the kidneys through the urine, causing bright yellow urine

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[3] [4] Clinical trials have demonstrated substantial reductions in hemoglobin A1c (up to 2.5% reduction from baseline) and body weight (up to 20% reduction from baseline) in the SURPASS and SURMOUNT clinical trial programs