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Mounjaro (tirzepatide) is widely prescribed for type 2 diabetes and commonly used off-label for weight loss due to its strong clinical results and convenient once-weekly dosing

In the mitochondrial inner membrane, flavin adenine dinucleotide (FAD)-dependent choline oxidase catalyzes the conversion of choline to betaine aldehyde, which is then converted to betaine by betaine aldehyde dehydrogenase in either the mitochondrial matrix or the cytosol (2)