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Another study examining 24-month-old NLRP3 knockout mice found that NLRP3 deficiency improved cardiac function by preventing metabolic dysregulation and mitigating other negative effects of cardiac aging [120]

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2013;4:e553

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Increased Surface Charge in the Protein Chaperone Spy Enhances Its Anti-Aggregation Activity

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as well as in humans with Crohns disease (Reference Taubert, Jung and Goeser45)

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