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Pain is present in the preclinical and initial stages of the disease and it is a cause of suffering and disability in patients with PD, causing a great impact on the quality of life and unfortunately, very often, pain goes unnoticed in clinical practice because usually the greatest attention is given to motor alterations

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CrossRef The Role of Adipokines in Pancreatic Cancer Qi Wang, Huizhi Wang, Yuntao Ding, Mengtian Wan, Min Xu Frontiers in Oncology.2022;[Epub] CrossRef Epigenetic Reprogramming of the Inflammatory Response in Obesity and Type 2 Diabetes Federica Zatterale, Gregory Alexander Raciti, Immacolata Prevenzano, Alessia Leone, Michele Campitelli, Veronica De Rosa, Francesco Beguinot, Luca Parrillo Biomolecules.2022

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Notably, the diffusion of FITC-dextran was not observed, confirming that the excreted glucose was not the result of diffusion, but occurred via the glucose transporter (Supplementary Fig