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2.5 Weighted gene co-expression network analysis The R package weighted gene co-expression network analysis (WGCNA) was used to identify the network of genes from the transcriptome data and seven physiological indices

1,3,53,54 Perhaps the most widely known trial evaluating LVRS is the National Emphysema Treatment Trial (NETT), which is considered one of the largest LVRS trials

Evidence from randomized clinical trials (2020 May 2025) highlights modest yet significant reductions in systolic and diastolic blood pressure with nutraceutical use, suggesting their complementary role alongside traditional antihypertensive regimens