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Intravenous rather than oral supplementation is recommended because it is likely to ensure higher levels of carnitine in the blood (L-carnitine has poor gastrointestinal bioavailability, which is further compromised by digestive dysfunction)

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Numerous preclinical studies have also suggested that tocotrienols might be beneficial in the prevention of chronic diseases (12)

Neurogenic orthostatic hypotension (OH) is another non-motor feature affecting one-third of PD individuals [166, 241]