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Lead toxicity Although the use of lead paint and leaded gasoline has been discontinued in the US, lead toxicity continues to be a significant health problem, especially in children living in urban areas

Disclosures: Katelynn Madill-Thomsen: Nothing to Disclose, Jeff Reeve: Nothing to Disclose, Sunil Kurian: Nothing to Disclose, Philip Halloran: Nothing to Disclose, Josh Levitsky: Nothing to Disclose 1311 ADVANCEMENTS IN LIVER TRANSPLANT OUTOMES FROM 1997 TO 2023 Fawaz Al Ammary 1 Abhinav Humar 2 Simeon Adeyemo 1 Kate Kriby 1 Ahmet Gurakar 3 , 1 University of California Irvine, 2 University of Pittsburgh Medical Center, 3 Johns Hopkins University Background: Improvment in liver transplant techniques and immunosuppression impact the lifespan of liver transplantation

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Increased ROS level above the cellular tolerability threshold results in apoptotic or necrotic cell death

Evaporation of the organic solvent leads to the formation of PLGA nanoparticles encapsulating the hydrophobic DDA-GSH-AuNCs