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Intracellular ACSL4 levels were reduced, while GPX4 levels were elevated (Fig

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5.2.5 Other Phase I Oxidation Enzymes In addition to CYPs, there are other non-CYP enzymes involved in Phase I metabolism, some of which have been highlighted above

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To verify that the binding of the C-terminal region of ATG2A to the ER membrane can inhibit autophagy, we generated a mutant of ATG2A by incorporating an ER targeting sequence (Tiwari and Weissman, 2001