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[iv] Challenges Associated With FIH Trials Since these studies represent the first administration of an investigational drug in humans, they are associated with inherent challenges, especially safety

The extracellular matrix breakdown Beyond collagen and elastin, the extracellular matrix (ECM) contains glycosaminoglycans (GAGs), proteoglycans, and structural glycoproteins that maintain skin hydration, volume, and smooth texture

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Supplying the vials together does not produce any outcome, and no claim is made that the compounds interact, synergise or converge on any shared result