glutathione biosynthesis in arabidopsis trichome cells Harnessing plant biochemistry for the production of useful compounds - Schilmiller - 2008 - The Plant Journal The Genetic Wiring of Plant

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This pool fuels essential processes such as DNA synthesis and mitochondrial respiration, but simultaneously predisposes cells to oxidative stress through iron-catalysed ROS generation (69, 70)

Collectively, these results implicate that -KG insufficiency potentially dampens TET activity

17 If pain does not rapidly respond to opioid analgesics or if opioids are not tolerated, the prompt addition of an adjunctive therapy should be considered

At present, it is not known whether the enhanced toxicity evident in rat and human liver slices when compared to mouse liver slices can be attributed to a species difference in formation of reactive intermediates, detoxification of these metabolites and/or to other considerations