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Bcl-2, Bcl-XL may confer resistance to Fas/Fas ligand mediated apoptosis in chronic lymphocytic leukemia (CLL) cells

SASP (Senescence-Associated Secretory Phenotype) signaling begins declining as the source cells are eliminated Weeks 2-6: Tissue microenvironments improve as SASP-driven inflammation decreases

This is in contrast to the requirement of special reagents such as a specific antibody to 4-iodobutyltriphenyl-phosphonium [61] or a cysteine-specific ICAT reagent [62]