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doi: 10.1002/fsn3.1636 253

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If you are homozygous (677T/T or 1298C/C) your enzyme efficiency can drop as low as 20% of normal

The activity of NRF2 is mediated by the KEAP1/CUL3/RBX1/E3 ubiquitin ligase complex [65]

First, it is essential to unravel in depth the causal association and temporal sequence between ferroptosis and neurodegeneration, as well as to explore cell type-specific roles of iron accumulation and ferroptosis across various neural populations