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This article synthesizes peer-reviewed research on GHK-Cus biological activity and its rapidly expanding applications in clinical aesthetics

Ye, Q, Law, T, Klippel, D, Albarracin, C, Chen, H, Contreras, A, Ding, Q, Huo, L, Khazai, L, Middleton, LP , Resetkova, E, Sahin, AA, Sun, H, Sweeney, K, Symmans, WF, Wu, Y, Yoon, EC, Krishnamurthy, S

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But once you escalate to 5 mg and beyond, the 30 mg vial becomes the clear winner in terms of value and convenience

By suppressing TGF-1 expression and preventing Smad2/3 phosphorylation, luteolin downregulates core ECM components, such as collagen I, fibronectin, and alpha-smooth muscle actin (-SMA), thereby limiting myofibroblast activation and pathological ECM accumulation