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As COPD progresses, with increased thickness of the airway wall, loss of alveolar attachments, and loss of lung elastic recoil, FEV 1 and FVC decrease

Common findings were: improved functional abilities (particularly walking) and significant pain relief associated with reduced intake of painkillers (including morphine-type medications, for those concerned)

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The other ferroptosis inducer, ML162 [161] and ML210, has the same effect as RSL3 in inducing ferroptosis and inhibiting the activity of GPX4