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The concentration of acrolein relative to the hydrate of 3-HPA was estimated to be less than 5% on the basis of 13 C signal intensity (100 mM 3-HPA, relaxation delay of 30 s)

This study was able to confirm the models biomimetic nature in replicating the in vivo fibrosis, given the embedment of fibroblasts in the hydrogel, which migrated into the clot and led to collagen type I deposition

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In cultured primary cells, Mn suppressed astrocytic glutamate handling and downregulated the expression of related genes 272