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2 Materials and methods 2.1 Protocol and registration This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement (Supplementary Table S1

3 Autoimmune diseases like inflammatory bowel disease and anti-phospholipid syndrome, as well as liver disease, kidney disease, pregnancy, and the use of oral estrogens (eg, hormone replacement therapy or high-dose oral birth control pills) are among the many potential causes of non-inherited thrombophilia

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It falls under the CMS J-code series for drugs administered by injection