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A prior study demonstrated that NLRP3 inflammasome activation induced the generation of mtROS, which directed the binding of GSDMD to the mitochondrial membrane, thus forming mitochondrial GSDMD pores and then causing the release of mtROS (82)

Chem Pharm Bull (Tokyo) 52: 12581261

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Laboratory investigations found that female mosquitoes infected with the w AlbB strain can become infertile as adults and may lack mature ovaries if they remain in the egg stage too long