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High-level TGF signalling is characteristic of many stroma-rich tumour types, including CMS4 CRC [3] and is a major metastasis-promoting signalling pathway in late-stage CRC [45]

In this review, we summarize the effective role of flavonoids in the treatment of liver disease (in Figure 3), and provide insights into their mechanism of action and targets

Hamelet J, Demuth K, Dairou J, Ledru A, Paul JL, Dupret JM, Delabar JM, Rodrigues-Lima F, Janel N: Effects of catechin on homocysteine metabolism in hyperhomocysteinemic mice

Their ability to regulate inflammatory responses and key signaling pathways make them potential therapeutic agents for treating renal fibrosis

Other methylated genes that are responsible for dictating bacterial cell shape, elongation and division are genes related to PG synthesis, such as ftsW , murA , murB , murC , murI , murJ , and mraY 191