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A separate concern runs across all four Day 1 compounds: the free base versus acetate salt form distinction

This weeks meeting revisits the discussion

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Cytokine Growth Factor Rev (2017) 36:7987

For instance, single nucleus sequencing of the entorhinal cortex of the hippocampus from AD brains reveals a repression of ApoE expression in astrocytic subpopulations and also oligodendrocyte precursor cells, but an increase in microglial expression (Grubman et al., 2019)