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Methods Experimental protocols Sixty C57BL/6J male mice (1820 g, 810 weeks, Changsheng Biotechnology Company, Liaoning, China) were housed and fed at the First Hospital of China Medical University, the Institute of Respiratory Disease, under quiet and controlled specific pathogen-free conditions

Sirtuin activation Sirtuins (SIRT1-7) are NAD+-dependent enzymes that regulate gene expression, mitochondrial biogenesis, inflammation, and stress responses

Because they boost energy and metabolism, the shots may also help patients shed unwanted pounds

From raw material selection to production and processing, we adhere to international GMP standards to ensure precise control at every stage

Many promising laboratory mechanisms fail to translate to meaningful human effects