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KPV (Lys-Pro-Val) is a naturally occurring tripeptide fragment of alpha-MSH that powerfully modulates inflammatory pathways by inhibiting NF-B activation, reducing pro-inflammatory cytokine production while supporting gut barrier integrity

Experimental investigations suggest the peptide may influence follicular activity through regulation of extracellular matrix remodelling, vascular support and dermal papilla function

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Reduced locomotor activity in 5xFAD mice by HDAC9 overexpression was also observed in the open field, as indicated by a decreased total distance travelled (Fig

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