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The applicant asserted that, while other treatments for FLT3 AML are available, VANFLYTA is the only treatment to exclusively target the FLT3-ITD mutation, thereby inhibiting further downstream FLT3 receptor signaling and blocking FLT3-ITD-dependent cell proliferation

The rats were deeply sedated with the same IP injection of xylazine (10 mg/kg) and ketamine (100 mg/kg) combination before cervical dislocation at the occipito-atlantal junction (Usende et al., 2020)

Biochem Biophys Res Commun 307: 973979, 2003

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Once transplanted into patients, these new beta cells began functioning naturally, regulating blood sugar levels and restoring the bodys ability to maintain glucose balance