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Description

mu-Opioid receptor down-regulation and cAMP-dependent protein kinase phosphorylation in a mouse model of chronic morphine tolerance

87 , e0112421 (2021)

Conservative Approach: Pregnancy: Doctor consultation absolutely necessary Breastfeeding: Limited research available Trying to conceive: Better to avoid until conception Conflicting Views: experts generally safe recommend complete avoidance FDA has no official guidelines 2