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Introduction The nourishment and growth of metastatic tumors require a significant supply of both nutrients and oxygen, which necessitates the development of an autonomous blood supply to the tumor microenvironment (TME) [1-3]

[28] Cases of fulminant liver failure reported with propylthiouracil have led to a regulatory warning, [29] and to guidelines recommending methimazole as the first line anti-thyroid agent

Conservative dosing initially (in research context) and close follow-up for signs of malignant transformation

E., Gould, D

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