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Cardiomegaly in the juvenile visceral steatosis (JVS) mouse is reduced with acute elevation of heart short-chain acyl-carnitine level after L-carnitine injection

doi: 10.3389/fmed.2026.1775447 Received 25 December 2025 Revised 02 March 2026 Accepted 24 March 2026 Published 17 April 2026 Volume 13 - 2026 Edited by Yulai Zhou, Yale University, United States Reviewed by Jeong-Ryeol Gong, Korea Advanced Institute of Science and Technology (KAIST), Republic of Korea Muralidharan Mani, University of Wisconsin-Madison, United States Updates Copyright 2026 Lu, Qian, Ma, Shao and Xie

Lipid-based formulations, including liposomes and solid lipid nanoparticles, enhance solubility and facilitate lymphatic transport, thereby increasing bioavailability