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Despite substantial interest and early successes, retatrutide remains investigational and is not yet approved for general medical use

But BPC 157 seems really safe

"Evidence of widespread metabolite abnormalities in Myalgic encephalomyelitis/chronic fatigue syndrome: assessment with whole-brain magnetic resonance spectroscopy"

IV Therapy for Cancer Support IV Methylene Blue + High Dose vitamin C 180 mins | 5 medical credits Methylene Blue combined with High-Dose Vitamin C has demonstrated potential as an adjunctive strategy in supportive oncology care

Volume loss is another driver, and fillers can lift folds when volume is the main issue, while copper peptides cannot replace lost volume in one area