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Recently, characterization of MGST2 has revealed similarities also to this enzyme regarding substrate specificity and third-of-the-sites-reaction mechanism 8, 9

Uncertainty of the effectiveness of modifying the de Moraes et al

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As a result, whereas in most somatic cells G6PD is subject to turnover, in red blood cells any G6PD molecule undergoing denaturation or proteolytic breakdown cannot be replaced (this condition is true, of course, not only for G6PD but also for most other red blood cell enzymes )