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Notably, optimized conjugates such as STEAP1-5a and CLL1-5b, designated as DAC 30 (Fig

2.3 Dysregulation of mitophagy The accumulation of fragmented and dysfunctional mitochondria resulting from excessive fission imposes a critical burden on the mitophagic clearance system

Importantly, most biological damages caused by RCS are related to -dicarbonyls (compounds with two adjacent reactive carbonyl groups), including glyoxal, methylglyoxal, 3-deoxyglucosone, 3-deoxyfructose

Chu D T, Phuong T N T, Tien N L B et al

Supplementation significantly increased serum magnesium concentration in the treatment group with no difference noted in the control group (Talebi 2013)