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It's a stimulant that affects the brain in much the same way as coffee

They used the Genotype Tissue Expression (GTEx) project, which has data from 46 types of human tissues of 717 individuals, and compared the gene expression in different tissues between smokers and people who never smoked

Beriot, N., Peek, J., Zornoza, R., Geissen, V

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Introduced by ITG Brands as part of their non-menthol lineup, the Blue King Box is designed for smokers who prefer the familiar KOOL brand in a traditional tobacco blend