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doi: 10.1111/j.1469-8749.2011.03971.x

Conclusion Despite significant progress in the management of cardiac iron overload in -thalassemia patients, cardiovascular disease remains the leading cause of death in this population

While MYC is a well-characterized human oncogene, systemic suppression of MYC as a targeted human longevity intervention is currently unproven and remains confined to transgenic mouse models and in vitro assays