Clinical observation on the effect of traditional Chinese medicine Wenyang Yiqi decoration on promoting clearing and reducing turbidity on the recovery of intestinal function after gastric cancer surgery
Cellular studies demonstrate increased lipolysis and fatty acid oxidation in differentiated adipocytes Animal models show reduced diet-induced obesity and improved insulin sensitivity with NNMT inhibition NAD+ metabolomics studies confirm restoration of cellular NAD+ and SAMe pools following NNMT blockade These findings are based on preclinical and clinical research
Effects of diet, lifestyle, chrononutrition and alternative dietary interventions on postprandial glycemia and insulin resistance
157 An NAFLD mouse model induced by a high-fat, high-sugar diet for 6 months exhibits hypercholesterolemia, glucose intolerance, and hyperinsulinemia, accompanied by severe hepatic macro- and microvesicular steatosis and human-like pericellular fibrosis, along with hepatic stellate cell activation, CD68 + macrophage infiltration, and elevated hepatic pro-inflammatory factors p65-NF-B, IL-6, and TNF- protein levels
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