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Was sie fanden: 70 % der Patienten in der GHK-Cu-Gruppe erzielten vollstndige Heilung vs 20 % in der Kontrollgruppe Schnelleres Heilungstempo , im Durchschnitt 4 Wochen vs 7 Wochen Bessere Narbenqualitt , weniger Kontrakturen, bessere Hautbarriere-Funktion Keine systemischen Nebenwirkungen Warum es relevant ist: Dies ist die klinische Validierung prklinischer mechanistischer Daten

Future integrative approaches combining molecular, experimental, and clinical investigations will be essential to establish safety, efficacy, and reproducibility in human diabetic wound care

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In vivo evidence is limited to a murine tooth extraction model treated with lipopolysaccharide injection where TNF-a retarded bone regeneration [196]

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