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However, the lack of effect on total nicotine exposure indicates VLNC noncompliance, suggesting that smokers with SMI may respond to a reduced-nicotine standard by substituting alternative forms of nicotine." "Additional doseresponse relationships have been detected on the number of cigarettes smoked per day when low and high nicotine Spectrum cigarettes are available

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Our results showing that the K6 score was strongly associated with ICD-10 diagnosis of anxiety or depressive disorders are consistent with previous findings [29, 32]

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The poll also shows that nearly a fourth of Kentucky adults have used electronic cigarettes